ALLERGEN-SPECIFIC IMMUNOTHERAPY: MODERN VIEW.LITERATURE REVIEW

Abstract

Relevance. The steady rise in allergic diseases over the past decades has challenged the scientific community to better
understand the mechanisms of allergic immune responses and to develop new therapeutic strategies to combat allergy
"epidemics".
Purpose: systematic search for modern scientific information on allergen-specific immunotherapy.
Search strategy: The search for scientific publications was carried out in databases, PubMed, ResearchGate,
specialized search engines Google Scholar by keywords. A total of 253 literary sources were found, of which 89 were
selected for analysis.
Result and conclusions. Allergen-specific immunotherapy has recently attracted increasing attention as a treatment for
a variety of allergic diseases. Specific immunotherapy is the only treatment that addresses the causes, not just the
symptoms, of allergies. This method of treatment was first introduced as subcutaneous immunotherapy, but later new
methods of introducing allergens, for example, such as sublingual and intralymphatic, began to be used. With the right
selection of patients, allergen-specific immunotherapy provides early control of allergy symptoms and long-term remission.
The decision to conduct allergen immunotherapy should be made on a case-by-case basis, taking into account individual
patient factors such as the severity of the disease, the effectiveness of preventive measures and pharmacological therapy.