FACTORS, ASSOCIATED WITH ONE YEAR SURVIVALAFTER STROKE IN KAZAKHSTAN: A COHORT STUDY

Abstract

Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence
on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the
problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey,
Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N =
937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests.
Independent associations of the studied factors with survival were studied using multivariable Cox
proportional hazard analysis. Crude and adjusted hazard ratios (RR) were calculated with 95%
confidence intervals (CI).
Results. Annual 12-years survival was 67.7% (95% CI: 64,6-70,6) in the study population. Age over
70 years (RR= 1,87; 95% CI: 1,09-3,20),Russian ethnicity (RR=1,69;95% CI 1,31-2,17), hemorrhagic
and subarachnoid hemorrhage (RR=3,06;95% CI 2,32-4,05) and (RR=3,72;95% CI 1,97-7,01)
respectively, history of myocardial infarction (RR=1,41;95% CI 1,03-1,94),а high NIHSS score with 12-
months survival.
Conclusions: Factors influencing survival of patients after stroke in Kazakhstan were identified. Our
results may be used for the development of therapeutic and rehabilitation measures to improve longterm survival after stroke.