QUALITY OF LIFE OF PATIENTS WITH CHRONIC PANCREATITIS

Abstract

Introduction. The quality of life (QoL) of patients with chronic pancreatitis (CP) can be affected by various factors, by identifying which it is possible to determine ways to improve rehabilitation for this pathology. Aim. To study the quality of life of patients with chronic pancreatitis. Materials and methods. Study design: prospective cross-sectional study. A sociological survey was conducted among 159patients with various forms of CP treated in gastroenterology department of the University Hospital of the Non-Profit Joint Stock Company "Semey Medical University" (UH NJSC "SMU") in the period 2022-2023years. To determine medical and social characteristics, a developed questionnaire for patients with pancreatitis was used. The QoL of patients was studied using the SF-36 questionnaire. To identify levels of depression and anxiety in patient’s questionnaires were used (Beck Depression Scale, Spielberg questionnaire). Statistical analysis was performed using SPSS software version 20.0, and results were considered statistically significant when p<0.05. Results. The QoL of patients with CP are reduced both in terms of physical (40.14±8.25) and psychological (44.85±8.75) components of health. Low QoL indicators on the scales “role physical functioning” (46.04±19.23), “role emotional functioning” (49.49±19.58) indicate a decrease in the index of comfortable existence. Influence of age and gender composition, social status, physical activity, exacerbation and duration of the disease, medical observation, concomitant diseases, and psychological status on certain criteria of QoL was established. Conclusions. Age 60 years or older, disability, unemployment, low physical activity¸ presence of concomitant fatty hepatosis, cholelithiasis, cholecystitis, obesity, depression, anxiety, frequent exacerbations, and duration of the disease for more than 10years, lack of medical supervision significantly reduces the QoL of patients with CP.