ANALYSIS OF THE CURRENT SITUATION ON THE AVAILABILITY OF INFORMATION ON ONGOING CLINICAL TRIALS IN THE REPUBLIC OF KAZAKHSTAN

Abstract

Availability of information about clinical trials (CTs) in the country is an important condition for sufficient transparency and quality of CTs. The purpose of this study was to analyze the availability of information about CTs in Kazakhstan. The main method was searching among publicly available sources on the internet. Data from four sources were found and analyzed: two Russian-language ones – the National Database of CTs of the National Center for Expertise of Medicines and Medical Devices and the Russian Federation Register “State Register of Medicines” with data on CTs in Kazakhstan; two Englishlanguage ones - the International Clinical Trials Database of the US National Library of Medicine ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform (ICTRP). Data from local ethical commissions were also taken into account. Based on the results of the analysis, the following main conclusions were made: English-language databases were more accessible and informative; the amount of information and its content was different in all four resources; all four resources had missing data. Based on this analysis, some recommendations were made to improve the availability of information about CTs in Kazakhstan.