THE EFFECT OF ENDOMETRIAL THICKNESS ON THE OUTCOMEOF ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS. REVIEW.

Abstract

Introduction. A thin endometrium recorded on ultrasound during ovarian stimulation, according to literature data, is
associated with a decrease in the frequency of pregnancy after in vitro fertilization (IVF), even in the absence of previous
surgical interventions in the uterine cavity or an infectious endometrial lesion. This literature review is devoted to the study of
the effect of endometrial thickness on the outcomes of assisted reproductive technologies.
The aim. To study the experience of foreign authors in studying the correlation of the outcomes of IVF programs with the
thickness of the endometrium at the time of embryo transfer.
Search strategy. The literature search was carried out using PubMed, Google Scholar, Medline databases over the past
10 years, and several sources from 1989, 1993 and 1996 containing conceptual information were also included. The search
was performed by keywords: «endometrial thickness», «thin endometrium», «assisted reproductive technologies», «in vitro
fertilization». English-language articles evaluating the correlation between the thickness of the endometrium and the
frequency of pregnancy, maternal and perinatal outcomes in women who underwent IVF were selected.
Results and conclusions. Analysis of these studies has shown that there is a natural correlation between the thickness
of the endometrium and the performance indicators of assisted reproductive technology programs. The thin endometrium
reduces the frequency of clinical pregnancy, and also adversely affects the outcome of pregnancy itself, increasing the risks
of miscarriage and premature birth.